Brief Communications Growth of White Matter in the Adolescent Brain: Role of Testosterone and Androgen Receptor
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چکیده
Jennifer S. Perrin,1 Pierre-Yves Hervé,1 Gabriel Leonard,2 Michel Perron,4 G. Bruce Pike,2 Alain Pitiot,1 Louis Richer,5 Suzanne Veillette,4 Zdenka Pausova,1,3 and Tomáš Paus1,2 1Brain and Body Centre, University of Nottingham, Nottingham NG7 2RD, United Kingdom, 2Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4, 3Centre de recherche, Centre hospitalier de l’Université de Montreal, Montreal, Quebec, Canada H2L 4M1, 4Le Groupe d’étude des conditions de vie et des besoins de la population (ÉCOBES), Collège d’enseignement général et professionnel (CÉGEP) Jonquiere, Jonquiere, Quebec, Canada G7X 3W1, and 5Department of Psychology, University of Quebec in Chicoutimi, Chicoutimi, Quebec, Canada
منابع مشابه
Growth of white matter in the adolescent brain: role of testosterone and androgen receptor.
The growth of white matter during human adolescence shows a striking sexual dimorphism; the volume of white matter increases with age slightly in girls and steeply in boys. Here, we provide evidence supporting the role of androgen receptor (AR) in mediating the effect of testosterone on white matter. In a large sample of typically developing adolescents (n = 408, 204 males), we used magnetic re...
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تاریخ انتشار 2008